Auto/biograficzne pęknięcie. Fragmenty dyskusji panelowej „Autobiografia na pograniczu gatunku i doświadczenia”
نویسندگان
چکیده
منابع مشابه
Intracellular Na+ Concentration ([Na+]i) Is Elevated in Diabetic Hearts Due to Enhanced Na+–Glucose Cotransport
BACKGROUND Intracellular Na(+) concentration ([Na(+)]i) regulates Ca(2+) cycling, contractility, metabolism, and electrical stability of the heart. [Na(+)]i is elevated in heart failure, leading to arrhythmias and oxidative stress. We hypothesized that myocyte [Na(+)]i is also increased in type 2 diabetes (T2D) due to enhanced activity of the Na(+)-glucose cotransporter. METHODS AND RESULTS T...
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Bumetanide-sensitive (BS) unidirectional fluxes of (36)Cl- or (22)Na+ were measured in internally dialyzed squid giant axons while varying the intra- or extracellular concentrations of Na+ and/or Cl-. Raising either [Cl-]i or [Na+]i resulted in a concentration-dependent reduction of the BS influx of both (36)Cl- and (22)Na+. Raising [Cl-]i above 200 mM completely blocked BS influxes. However, r...
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ژورنال
عنوان ژورنال: Autobiografia
سال: 2015
ISSN: 2353-8694
DOI: 10.18276/au.2015.2.5-10